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Patients with peripheral arterial disease (PAD) have decreased lower extremity arterial perfusion which is commonly referred to as "poor circulation." In most cases of PAD, atherosclerotic plaques narrow the arterial flow lumen which restricts blood flow to the distal extremity. Reduced blood flow can cause thigh or calf pain with walking due to temporary ischemia of the leg muscles during.


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2. Introduction on Topic. Peripheral arterial disease (PAD) is one of the clinical types of atherosclerotic diseases. For this reason, particular attention should be given to its frequent diagnosis in elderly individuals, with particular prevalence of PAD-affected patients in socially and economically advanced countries [1,2].PAD is often under-diagnosed, although we are in possession of non.


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Further studies are needed to clarify the pathology of PAD. Pathophysiology.. optimal programme design and implementation have been reviewed in detail 106,133,134,135,136.


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Abstract. Context.โ€”Eighty-two million surgical pathology and cytology reports were issued in the United States during 2007; a subset of these reports will be misunderstood by readers. Recent attention has focused on standardizing the content of pathology reports, particularly for common malignancies, to facilitate transmission of required information. Comparatively little attention has been.


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Subsequently, the tools for assessing each of these components is discussed, including, where available, the evidence to contextualize these tools to PAD pathology as well as physical function and CVD outcomes. The goal of this review is to guide researchers to the appropriate tools with respect to their methodological design.


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Peripheral arterial disease (PAD) in the legs or lower extremities is the narrowing or blockage of the vessels that carry blood from the heart to the legs. It is primarily caused by the buildup of fatty plaque in the arteries, which is called atherosclerosis. PAD can happen in any blood vessel, but it is more common in the legs than the arms.


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2. Epidemiology of PAD. The prevalence of PAD is estimated to be 10%-25% in people aged โ‰ฅ55 years and increases to approximately 40% in community populations aged >80 years [4,5].Approximately 4-8 million people are affected by PAD in the United States of America [6,7,8].In Germany around 1.8 million people have symptomatic PAD and each year between 50,000 to 80,000 patients develop CLI.


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The adoption of digital pathology follows a cycle similar to other new disruptive technologies, known as the technology adoption lifecycle or diffusion of innovation 1 (Fig. 1).This curve follows.


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Modern Pathology is an international journal owned by the United States & Canadian Academy of Pathology (USCAP). Modern Pathology aims to provide an authoritative platform for publishing the highest quality clinical and translational research studies in pathology. Original manuscripts are the main focus of Modern Pathology.


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PAD is often underdiagnosed or underestimated, although specificity in diagnosis is shown by an ankle/brachial approach, and the high cardiovascular event risk that affected the PAD patients. A number of pathophysiologic pathways operate in chronic arterial ischemia of lower limbs, giving the possibility to improve therapeutic strategies and.